Status:
COMPLETED
Effect Of Non-Surgical Periodontal Treatment On Lipoxin a4 Levels
Lead Sponsor:
Ordu University
Conditions:
Periodontitis
Eligibility:
All Genders
25-65 years
Phase:
NA
Brief Summary
The aim of this study was to evaluate the levels of lipoxin A4 (LXA4), prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in gingival crevicular fluid (GCF) and saliva in individuals with periodontal h...
Eligibility Criteria
Inclusion
- Have at least 20 natural teeth, excluding third molars.
- Chronic periodontitis patients had at least two non-adjacent sites per quadrant with probing depth (PD) ≥ 5 mm and clinical attachment level (CAL) ≥ 5 mm with gingival inflammation, and alveolar bone loss affecting \>30% of the teeth, as detected on clinical and radiographical examinations.
- Periodontally healthy control group had no sign of gingival inflammation, no PD \> 3mm and no evidence of attachment or bone loss.
Exclusion
- History of systemic disease.
- Regular use of any drugs which can effect the immune system or inflammatory response in the 6 months preceding the start of the study.
- Periodontal treatment during last 6 months that could affect periodontal status.
- Smoking.
- History of radiotherapy or chemotherapy.
- Ongoing orthodontic treatment.
- Aggressive periodontitis.
- Current pregnancy, lactation or menopause.
Key Trial Info
Start Date :
October 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2018
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04053660
Start Date
October 1 2017
End Date
December 31 2018
Last Update
August 12 2019
Active Locations (1)
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1
Ordu University
Ordu, Turkey (Türkiye), 52200