Status:
COMPLETED
Pistachios Blood Sugar Control, Heart and Gut Health
Lead Sponsor:
Penn State University
Conditions:
Type 2 Diabetes
Cardiovascular Diseases
Eligibility:
All Genders
30-65 years
Phase:
PHASE2
Brief Summary
A two-period randomized crossover study will be conducted to evaluate the effect of nighttime pistachio consumption (i.e., after dinner and before sleep) on fasting blood sugar levels, longer-term blo...
Detailed Description
A two-period randomized crossover trial will be conducted. Participants will be randomized to receive each treatment for 12 weeks followed by a minimum 4-week wash-out period. During the pistachio tre...
Eligibility Criteria
Inclusion
- BMI ≥25 and ≤45 kg/m2
- Fasting plasma glucose 100 - 125 mg/dL
- non-Smoking
Exclusion
- Diagnosed diabetes or fasting glucose \>126 mg/dl
- Systolic blood pressure \>160mmHg or diastolic blood pressure \>100mmHg)
- Prescribed anti-hypertensive, lipid lowering or glucose lowering drugs
- Established cardiovascular disease, stroke, diabetes, liver, kidney or autoimmune disease or inflammatory conditions
- Use of supplements (psyllium, fish oil, soy lecithin, phytoestrogens) and botanicals and not willing to cease for the duration of the study
- Women who are pregnant, lactating, planning to become pregnant or have given birth in the past year
- Weight loss of \>=10% of body weight within the 6 months prior to enrolling in the study
- Smoking or use of any tobacco products
- Allergy/intolerance/sensitive to pistachios
- Consumption of \>14 alcoholic drinks/week
- Shift-workers and those who cannot consume a snack in the evening
Key Trial Info
Start Date :
September 9 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 17 2022
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04056208
Start Date
September 9 2019
End Date
November 17 2022
Last Update
August 18 2023
Active Locations (1)
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1
Pennsylvania State University
University Park, Pennsylvania, United States, 16802