Status:

COMPLETED

Clinical and Radiological Outcomes of Posterior Cervical Fusion with Medtronic Infinity Occipitocervical-Upper Thoracic (OCT) System

Lead Sponsor:

Ohio State University

Collaborating Sponsors:

Medtronic

Conditions:

Degenerative Disc Disease

Eligibility:

All Genders

18+ years

Brief Summary

This study is being done to prospectively collect data on subjects having posterior cervical fusion surgery using the Medtronic Infinity system. Researchers plan to collect information from patients h...

Detailed Description

This is a prospective single arm study of clinical and radiological outcomes as well as surgical data from posterior cervical fusion for treating degenerative disc disease (DDD). Patients undergoing p...

Eligibility Criteria

Inclusion

  • ≥ 18 years old
  • Symptomatic multi-level degenerative spondylosis necessitating posterior cervical arthrodesis in the subaxial cervicothoracic spine (between C2-upper thoracic).
  • Surgery performed within the Department of Neurological Surgery at The Ohio State University Wexner Medical Center (OSUWMC)

Exclusion

  • Traumatic injury
  • Co-morbidity requiring medication use that may interfere with bone or soft tissue healing (i.e., high dose oral or parenteral glucocorticoids, immunosuppressive agents, methotrexate) - at discretion of investigator
  • Severe co-morbidities (e.g., heart, respiratory, or renal disease)
  • Clinically diagnosed osteoporosis
  • Recent (\<3 yrs) or co-incident spinal tumor or infection
  • Concurrent involvement in another investigational drug or device study that could confound study data
  • History of substance abuse (recreational drugs, prescription drugs or alcohol) that could interfere with protocol assessments and/or with the subject's ability to complete the protocol required follow-up
  • Subjects who are pregnant or plan to become pregnant in the next 24 months
  • Prisoner
  • Other contraindications for Medtronic Infinity System

Key Trial Info

Start Date :

September 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 13 2024

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT04056520

Start Date

September 1 2019

End Date

December 13 2024

Last Update

March 21 2025

Active Locations (1)

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1

The Ohio State University Wexner Medical Center

Columbus, Ohio, United States, 43210