Status:

UNKNOWN

Analgesic Effect of Adding Thoracic Paravertebral Nerve Blocks to Modified PEC Block in Breast Cancer Surgery

Lead Sponsor:

Mahidol University

Conditions:

Breast Cancer Female

Pain, Postoperative

Eligibility:

FEMALE

18-80 years

Phase:

NA

Brief Summary

To compare efficacy and safety of adding thoracic paravertebral nerve blocks to modified PEC block versus modified PEC block only in breast cancer surgery. This study evaluate systemic opioid requirem...

Detailed Description

Regional anesthesia has been used and studied extensively in breast surgery as an opioid-sparing strategy, with block of the intercostal supply by thoracic paravertebral block (TPVB) becoming a popula...

Eligibility Criteria

Inclusion

  • American Society of Anesthesiologists (ASA) grade I-III
  • Aged ≥ 18-80 years old
  • Elective unilateral total mastectomy with sentinel lymph node biopsy or lymph node dissection

Exclusion

  • Patient refusal
  • Language barrier or inability to communicate with the operating team
  • Allergy to local anesthetic
  • Bleeding disorder
  • Previous breast surgery or thoracic radiation therapy
  • BMI ≥ 30
  • Patient who can not understand the proper use of intravenous patient-controlled analgesia machine or who has the problem with communication
  • Chronic pain patient

Key Trial Info

Start Date :

August 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04056676

Start Date

August 1 2019

End Date

March 1 2022

Last Update

May 24 2021

Active Locations (1)

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Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok Noi, Bangkok, Thailand, 10700