Status:
COMPLETED
Targeted Noninvasive Brain Stimulation to Improve Hand Dexterity in Stroke Patients
Lead Sponsor:
Kessler Foundation
Conditions:
Stroke
Eligibility:
All Genders
18-75 years
Brief Summary
This study will investigate the use of High-definition Transcranial Direct Current Stimulation (HD-tDCS) in the functional improvement of hand dexterity while performing music-assisted hand exercises.
Detailed Description
Stroke is a serious medical and health problem in the US, and most of the stroke patients suffer from upper-limb motor deficits including weakened hand dexterity. As upper-limb motor functions are cru...
Eligibility Criteria
Inclusion
- Aged between 18-75 years
- Clinically diagnosed with hemiparetic stroke (weakness on one side - either left or right side of the body)
- Have had a stroke for more than 6 months
- Have weakness in moving the fingers of the affected hand
- Able to understand and perform the instructions that are part of the tDCS-MusicGlove testing and intervention.
- Willing and able to participate in and travel to Kessler Foundation for the screening session, MRI session, and tDCS-MusicGlove sessions.
- Able to sit and be active for 1.5 hours during the session without cardiac, respiratory and/or pain disturbances as assessed during the screening visit.
- Able to provide informed consent.
- Medically stable and not planning for a major change in medications for at least 4 weeks
Exclusion
- Unable to move the hand because of muscle stiffness (scoring 3 or more on the Ashworth scale)
- Have lost the sensation of hand movement
- Have a history of alcohol abuse and/or illicit drug use
- Have a history of smoking within the past 5 years
- Have a problem with the eyesight that would make it difficult to notice the changing instructions on a computer screen
- Currently enrolled in another research study that might affect this research study
- A history of epilepsy (including family members who are diagnosed with epilepsy)
- An active history of migraine or chronic headache
- A history of mental illness (e.g. schizophrenia, anxiety, depression, and PTSD)
- Past or current history of treated ringing in the ears known as tinnitus or severe hearing problems
- Have a tattoo with metal-based ink in the head or neck.
- Have severe skin damage on the scalp
- Afraid of confined spaces (claustrophobic)
- Have metallic implants, including intracranial electrodes, surgical clips, shrapnel or a pacemaker.
- Currently taking medications that increase the risk of seizures
- Pregnant
Key Trial Info
Start Date :
October 28 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 31 2023
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT04058288
Start Date
October 28 2019
End Date
May 31 2023
Last Update
June 12 2023
Active Locations (1)
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1
Kessler Foundation
West Orange, New Jersey, United States, 07052-1424