Status:

COMPLETED

Risk Prediction Models for Adverse Maternal and Neonatal Outcomes in Preeclampsia

Lead Sponsor:

Mpilo Central Hospital

Conditions:

Severe Preeclampsia

Eligibility:

FEMALE

14+ years

Brief Summary

This proposal describes a single centre retrospective cross-sectional study which will address the need to further develop and test statistical risk prediction models for adverse maternal and neonatal...

Detailed Description

Hypertensive disorders in pregnancy are a leading cause of maternal and perinatal morbidity and mortality, especially in low-resource settings. Identifying mothers and babies at greatest risk of compl...

Eligibility Criteria

Inclusion

  • Participants will be included in the study if they have a diagnosis of severe preeclampsia.
  • Severe preeclampsia will be defined as high blood pressure (systolic blood pressure (SBP) ≥160, diastolic blood pressure(DBP) ≥110mmHg) and or either severe headaches, epigastric pains and deranged biochemical/haematological blood indices.
  • Both singleton and twin/higher order pregnancies will be included.

Exclusion

  • Women with mild or moderate preeclampsia or less than 20 weeks' of gestation and those with epilepsy will be excluded from the study.

Key Trial Info

Start Date :

November 12 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 31 2021

Estimated Enrollment :

549 Patients enrolled

Trial Details

Trial ID

NCT04058405

Start Date

November 12 2018

End Date

August 31 2021

Last Update

September 10 2021

Active Locations (1)

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Mpilo Central Hospital

Bulawayo, Matabeleland, Zimbabwe, +263

Risk Prediction Models for Adverse Maternal and Neonatal Outcomes in Preeclampsia | DecenTrialz