Status:
TERMINATED
Mandibular Furcation II Regeneration
Lead Sponsor:
University of Oslo
Conditions:
Furcation Defects
Periodontal Diseases
Eligibility:
All Genders
20+ years
Phase:
PHASE4
Brief Summary
Teeth with furcation grade II defects will be treated with open flap debridement and regenerative therapy with biphasic calcium phosphate combined with either enamel matrix proteins or a collagen memb...
Eligibility Criteria
Inclusion
- Subject must be ≥ 20 years
- Subject must have periodontal disease as determined by the World Workshop 2017 criteria
- Subjects must be undergoing periodontal treatment or follow-up and present 1 or more pair of bilateral mandibular molars affected by furcation involvement grade II with PPD \>4 mm, and the furcation fornix must be below a tangential line from the distal to mesial interproximal crestal bone level
- Competent to give consent
Exclusion
- The following must not be present at the time of enrolment;
- Previous radiotherapy to the jaws, current use of chemotherapy, systemic long-term corticosteroid treatment
- Present or past use of bisphosphonate treatment
- Pregnant or nursing subjects
- Patients classified as \> class 2 according to the ASA (American Society of Anesthesiologists) physical status classification
- Previous surgical therapy of included furcation defects
- Inability to comprehend and respond to the quality of life questionnaire
- Dental restorations or prosthesis involving the furcation area
- Root fractures or suspected infractions
- Caries lesions in the furcation area
- No systemic antibiotic treatment within 3 months prior to intervention
Key Trial Info
Start Date :
October 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 27 2023
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT04059445
Start Date
October 15 2019
End Date
November 27 2023
Last Update
November 30 2023
Active Locations (1)
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1
Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo
Oslo, Norway, 0455