Status:
COMPLETED
Mercury Metabolism by Bacteria in Humans
Lead Sponsor:
University of Rochester
Collaborating Sponsors:
National Institute of Environmental Health Sciences (NIEHS)
Conditions:
Mercury--Toxicology
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate how the bacteria in your gut can improve the break-down and de-toxification of non-harmful levels of a naturally occurring form of mercury (methylmercury) that...
Detailed Description
The overall objective of this study is to investigate the role of gut microbes in mediating how humans metabolize and excrete the environmental neurotoxicant methylmercury (MeHg). Exposure to MeHg thr...
Eligibility Criteria
Inclusion
- Subjects must be 18-80 years in age.
- Subjects must be in good general health based on self-reported health status, with the exception of self-reported conditions listed in the exclusion criteria.
- Subject must be willing to comply with study procedures.
Exclusion
- Known allergy to fish.
- Pregnant or lactating women.
- Use of hair dyes or chemical treatments within the prior month and/or intent to use such treatments during the two trial periods. (Hair treatment during the washout period up to one month prior to the second trial is acceptable).
- Known gastrointestinal or renal disorders.
- Subjects with diminished mental capacity.
- Use of antibiotics within two months leading up to the study.
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2023
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT04060212
Start Date
October 1 2019
End Date
August 31 2023
Last Update
October 4 2023
Active Locations (1)
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1
University of Rochester Medical Center
Rochester, New York, United States, 14642