Status:

UNKNOWN

Identification of Novel Biomarkers of Response to Systemic Treatments in Renal Cell Cancer

Lead Sponsor:

CCTU- Cancer Theme

Conditions:

Carcinoma, Renal Cell

Eligibility:

All Genders

18+ years

Brief Summary

This research study aims to investigate changes inside kidney cancers (also known as Renal Cell Carcinoma or RCC), and in normal kidney surrounding the tumour, when patients are treated with systemic ...

Detailed Description

This research study aims to investigate changes inside kidney cancers, and in normal kidney surrounding the tumour, when patients are treated with systemic therapy. Systemic treatment is widely used a...

Eligibility Criteria

Inclusion

  • Aged 18 years or older
  • Diagnosis of renal cell cancer (any stage).
  • Patient received systemic treatment for their renal cancer at Cambridge University Hospitals NHS Foundation Trust.
  • Patients must have consent in place, for the use of tissue and imaging to be used for the purposes of clinical research;
  • Use of tissue not required for their diagnosis or treatment to be stored and used for the purposes of clinical research, which may include genetic research.
  • Use of relevant sections of their medical records, or by relevant regulatory authorities, where my tissue is being used for research, giving permission for those individuals to have access to their medical records.
  • Participants must also meet at least one of the following criteria to be eligible:
  • For tissue analysis: Patient must have tumour tissue and/or normal adjacent kidney stored (either as formalinfixed paraffin-embedded tissue, or as 'fresh frozen' tissue).
  • For imaging analysis: Patient must have had at least 1 scan (either CT or MRI) within 28 days of starting treatment with systemic treatment for their cancer.

Exclusion

  • None

Key Trial Info

Start Date :

January 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 1 2022

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT04060537

Start Date

January 1 2020

End Date

January 1 2022

Last Update

August 19 2019

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