Status:

COMPLETED

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Lead Sponsor:

Ocular Therapeutix, Inc.

Conditions:

Open Angle Glaucoma and Ocular Hypertension

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

To evaluate the long term safety of repeat dose OTX-TP, a sustained release travoprost drug product, placed in the canaliculus of the eyelid in the treatment of subjects with open-angle glaucoma or oc...

Eligibility Criteria

Inclusion

  • Had prior bilateral treatment and completion, through a minimum of week 12, of the OTX-16-002 trial
  • Are informed of the nature of the study and subject is able to comply with study requirements and visit schedule for one year
  • Have provided written informed consent, approved by the appropriate Institutional Review Board

Exclusion

  • Had more than 1 replacement, per eye, during participation in the OTX-16-002 trial
  • Had punctal or canaliculi related adverse events during the OTX-16-002 trial which required discontinuation (e.g., canaliculitis)
  • Used prohibited medications during the OTX-16-002 study, or the period between OTX-16-002 and this trial (with the exception of short term medication used to treat an adverse event or rescue therapy)
  • Missed more than 2 visits during participation in the OTX-16-002 trial

Key Trial Info

Start Date :

July 10 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 22 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04061044

Start Date

July 10 2018

End Date

September 22 2020

Last Update

June 9 2023

Active Locations (1)

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1

ApexEye

Cincinnati, Ohio, United States, 45242