Status:

COMPLETED

The Effects of Changing Light Levels on Contrast Sensitivity in Patients With Glaucoma

Lead Sponsor:

Portsmouth Hospitals NHS Trust

Conditions:

Glaucoma

Eligibility:

All Genders

40+ years

Brief Summary

The study is a prospective observational study where participants will be recruited from the Ophthalmology department (Outpatient department, Eye Casualty). Only one research visit will be required. P...

Detailed Description

The purpose of our, real world study is to explore contrast sensitivity differences after changes in ambient light setting in patients with glaucoma compared with controls (patients with ocular hypert...

Eligibility Criteria

Inclusion

  • • Male or Female, aged 40 years or above.
  • Diagnosis of glaucoma (including primary open angle glaucoma, pigment dispersion syndrome, pseudoexfoliation, normal tension glaucoma, chronic angle closure glaucoma, narrow angle glaucoma) or ocular hypertension
  • Willing and able to give informed consent for participation in the study.
  • Best Corrected Visual Acuity equal or better than 6/12 as measured with the Snellen Chart

Exclusion

  • • Neovascular, uveitic, acute angle closure glaucoma
  • Non-glaucomatous ocular disease such as AMD, Diabetic retinopathy, Inherited eye diseases
  • Visually significant cataracts (Distance VA ≤ 6/12 (0.30 LogMAR) and grade ≥ grade 2 nuclear sclerosis.)
  • Current use of miotic glaucoma medication
  • Incisional or laser eye surgery within 3 months of enrolment
  • Severely impaired cognition
  • Self-reported physical ability limiting function (e.g. stroke)
  • Unreliable visual fields (SITA Standard or SITA Fast: fixation losses \>20% or false-positive errors \>33% or false-negative errors \>33%)

Key Trial Info

Start Date :

November 20 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 16 2021

Estimated Enrollment :

115 Patients enrolled

Trial Details

Trial ID

NCT04061343

Start Date

November 20 2018

End Date

March 16 2021

Last Update

April 7 2023

Active Locations (1)

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Portsmouth Hospitals NHS Trust

Portsmouth, Hampshire, United Kingdom, PO6 3LY

The Effects of Changing Light Levels on Contrast Sensitivity in Patients With Glaucoma | DecenTrialz