Status:
UNKNOWN
Postoperative Renal Failure in Cardiac Surgery PMSF-PVC Gradient Study
Lead Sponsor:
University Hospital, Strasbourg, France
Conditions:
Scheduled Heart Surgery
Valve Replacement
Eligibility:
All Genders
18+ years
Brief Summary
Acute renal failure is a frequent and severe postoperative complication of cardiac surgery performed under extracorporeal circulation. It is an independent risk factor for mortality and significantly...
Eligibility Criteria
Inclusion
- age\> 18 years
- subject having signed an informed consent
- scheduled heart surgery:
- Valve replacement
- Coronary artery bypass
Exclusion
- Any urgent surgery or redux
- Severe preoperative chronic renal failure (stage III) defined by GFR \<30ml / min
- Existence of rhythm disorders (permanent ACFA) or serious cardiac conduction disorders, patients with Pacemaker
- Preoperative alteration of left ventricular ejection fraction with LVEF \<40%
- Major haemodynamic instability with refractory shock defined by dobutamine ≥10μg / kg / min and / or norepinephrine ≥ 1μg / kg / min and / or epinephrine ≥ 0.2μg / kg / min.
- Intra-aortic versus assisted pelvic balloon
- Contraindication to femoral arterial catheterization
- Subject under the protection of justice, subject under guardianship or under tutorship
- Impossibility of giving the subject informed information (subject in emergency situation, difficulties in understanding the subject)
Key Trial Info
Start Date :
February 21 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2020
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT04062786
Start Date
February 21 2019
End Date
February 1 2020
Last Update
August 20 2019
Active Locations (1)
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1
Les Hôpitaux Universitaires de Strasbourg
Strasbourg, France, 67091