Status:

COMPLETED

Glucose-homeostasis After Endoscopic Sleeve Gastroplasty

Lead Sponsor:

Insel Gruppe AG, University Hospital Bern

Conditions:

Obesity, Morbid

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Endoscopic sleeve gastroplasty (ESG) is a transoral endoscopic procedure that creates a tubular sleeve along the lesser curvature with a gastric volume of approximately 30%. Summarizing the available ...

Detailed Description

Endoscopic sleeve gastroplasty (ESG) is a transoral endoscopic procedure that utilizes full-thickness sutures extending from the prepyloric antrum to the gastroesophageal junction, creating a tubular ...

Eligibility Criteria

Inclusion

  • Planned ESG
  • Written informed consent
  • Male or female sex
  • Age 18-65 years
  • BMI ≥ 40 kg/m2 OR
  • BMI ≥ 35 kg/m2 and obesity-related comorbidities except type 2 diabetes

Exclusion

  • Type 1 or Type 2 Diabetes
  • Type 2 Diabetes according to pathological OGTT at visit 2
  • Mandatory use of medical drugs that influence glucose metabolism
  • Participant had bariatric procedures other than ESG
  • Abdominal surgery influencing glucose metabolism
  • Moderate to severe chronic kidney, liver, or pancreatic disease
  • Pregnancy or breastfeeding
  • Physical or psychological disease likely to interfere with the normal conduct of the study and interpretation of the study results as judged by the investigator

Key Trial Info

Start Date :

January 30 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 9 2023

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04063098

Start Date

January 30 2020

End Date

May 9 2023

Last Update

April 27 2025

Active Locations (1)

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Department of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

Bern, Switzerland, 3010

Glucose-homeostasis After Endoscopic Sleeve Gastroplasty | DecenTrialz