Status:
SUSPENDED
Effects of Remote Ischemic Pre-Conditioning in Moyamoya Disease Patients
Lead Sponsor:
Beijing Tiantan Hospital
Collaborating Sponsors:
Peking University International Hospital
Conditions:
Moyamoya Disease
Remote Ischemic Preconditioning
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
In the present study, investigators evaluated whether RIPC reduce the major neurological complications in adult moyamoya disease patients undergoing encephaloduroarteriosynangiosis (EDAS).
Detailed Description
BACKGROUND: Brain ischemia and injury contributed to perioperative morbidity and mortality in revascularization surgery. Remote ischemic preconditioning (RIPC), brief periods of ischemia followed by r...
Eligibility Criteria
Inclusion
- Patients who diagnosed with moyamoya disease
- Adults 18 to 65 years of age
- The onset symptoms manifested as ischemic symptoms (TIA or stroke) or atypical symptoms (headache, epilepsy or asymptomatic)
- Able to receive the necessary imaging examination
- Patients who pre-agreed to the study
Exclusion
- Prior cerebral hemorrhage history
- Other brain or cerebrovascular disease
- Previous history of revascularization surgery
- Dependent (mRS \> 2)
- Receive other type of revascularization surgery
- Peripheral blood vessel disease (especially subclavian arterial and upper limb artery stenosis or occlusion).
- Patients who do not agree with the study
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2024
Estimated Enrollment :
328 Patients enrolled
Trial Details
Trial ID
NCT04064658
Start Date
October 1 2019
End Date
April 1 2024
Last Update
September 19 2019
Active Locations (2)
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1
Beijing Tiantan Hosiptal
Beijing, Beijing Municipality, China, 100070
2
Peking University International Hospital
Beijing, Beijing Municipality, China, 102206