Status:

RECRUITING

GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET

Lead Sponsor:

The University of Hong Kong

Conditions:

Subfertility

Eligibility:

FEMALE

18-42 years

Phase:

PHASE3

Brief Summary

The objectives of this study are to compare the efficacy of the dual trigger group vs the hCG trigger group on the live birth rate in women undergoing IVF and the efficacy of the agonist in LP group v...

Detailed Description

Trial design: A randomised, double-blinded and placebo controlled trial will be performed in IVF cycles and another randomised, double-blinded and placebo controlled trial will be performed in FET cy...

Eligibility Criteria

Inclusion

  • IVF
  • Inclusion criteria:
  • \- Women aged \<43 years at the time of IVF treatment
  • Exclusion criteria:
  • Preimplantation genetic diagnosis treatment
  • Use of donor oocytes or donor embryos
  • Hydrosalpinx shown on pelvic scanning and not surgically treated
  • Women at risk of OHSS
  • FET
  • Inclusion criteria:
  • Women aged \<43 years at the time of IVF treatment
  • Replacing early cleavage embryos or blastocysts after thawing
  • FET in natural cycles
  • Exclusion criteria:
  • Frozen early cleavage embryos thawed and cultured to blastocysts prior to transfer as requested by the patient
  • Preimplantation genetic diagnosis treatment
  • Use of donor oocytes or donor embryos
  • Hydrosalpinx shown on pelvic scanning and not surgically treated

Exclusion

    Key Trial Info

    Start Date :

    September 1 2019

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    March 30 2025

    Estimated Enrollment :

    784 Patients enrolled

    Trial Details

    Trial ID

    NCT04064840

    Start Date

    September 1 2019

    End Date

    March 30 2025

    Last Update

    December 6 2024

    Active Locations (1)

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    1

    Department of Obstetrics and Gynaecology

    Hong Kong, Hong Kong, China