Status:

UNKNOWN

Nutritional Deficiencies About Recurrent Miscarriage

Lead Sponsor:

Peking Union Medical College Hospital

Conditions:

Abortion, Habitual

Nutritional Status

Eligibility:

FEMALE

Up to 35 years

Brief Summary

The study plans to recruit patients with recurrent miscarriage and detect their niacin, thiamine, vitamin A, vitamin B6, vitamin B12, vitamin D levels in plasma, evaluating if some lack exists.

Detailed Description

Dr. Shi Hongjun from West Lake University has confirmed in a mouse model that a decrease in maternal niacin levels caused by a low niacin diet can lead to stillbirth(HJ Shi, et al. 2017). Due to the l...

Eligibility Criteria

Inclusion

  • Research group 1: Recurrent abortion group: women of childbearing age who have spontaneous abortion within 20 weeks of pregnancy for 2 or more consecutive times.
  • Control group: 1) Women of childbearing age who had a normal pregnancy history and are not in pregnancy status now. 2) Women of childbearing age in general examination.

Exclusion

  • patients with confirmed causes unrelated to nutritional deficiencies, including
  • Both husband and wife have been diagnosed with chromosomal abnormalities or fetal chorionic chromosomal abnormalities;
  • The patient has been diagnosed with uterine abnormalities;
  • vaginal bacterial infection or chlamydial infection;
  • antiphospholipid antibody syndrome;
  • Other immune system diseases (hypothyroidism, PCOS, hyperprolactinemia);
  • ovarian function decline (FSH\>10mIU/ml);
  • Cervical insufficiency5.3 Exit criteria:
  • After being selected, the researcher was withdrawn due to various considerations.

Key Trial Info

Start Date :

August 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2022

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT04064931

Start Date

August 1 2019

End Date

November 1 2022

Last Update

March 15 2022

Active Locations (1)

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Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China, 100730

Nutritional Deficiencies About Recurrent Miscarriage | DecenTrialz