Status:

COMPLETED

TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries

Lead Sponsor:

Recep Tayyip Erdogan University Training and Research Hospital

Conditions:

High Caries Risk

Low Caries Risk

Eligibility:

All Genders

25-44 years

Brief Summary

The aim of this study is to examine the effects of TAS1R1, TAS1R3, TLR2, TLR4, CA6, gene polymorphism on caries risk in adults.

Detailed Description

To date, genes can be grouped into categories based on the factor influencing dental caries. The major candidate gene categories to date include enamel formation genes, immune response genes, genes re...

Eligibility Criteria

Inclusion

  • adult be between 25 and 44 years old
  • subject has DMFT (Decayed, Missing, Filled, Permanent Tooth) ≥ 5, or, DMFT ≥14
  • same oral health, diet and socioeconomic status

Exclusion

  • systemic or genetic disorders
  • orthodontic appliances
  • pregnant women

Key Trial Info

Start Date :

January 15 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 20 2019

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04066101

Start Date

January 15 2018

End Date

November 20 2019

Last Update

April 15 2021

Active Locations (1)

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Recep Tayyip Erdogan University

Rize, Turkey (Türkiye), 53000