Status:

UNKNOWN

Efficacy of Monotherapy vs Combination Therapy of Corticosteroids With GCSF in Severe Alcoholic Hepatitis Patients.

Lead Sponsor:

Institute of Liver and Biliary Sciences, India

Conditions:

Alcoholic Hepatitis

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The patients of Severe Alcoholic Hepatitis (SAH) will be included in study based on inclusion and exclusion criteria. The patients will be then randomized in 3 groups for therapy. They will receive ei...

Eligibility Criteria

Inclusion

  • Severe alcoholic hepatitis patients \[Maddrey's score \> 32\] aged between 18 to 65 years.

Exclusion

  • Presence of active infections
  • Acute Gastrointestinal bleed
  • Hepatorenal syndrome
  • Patient unwilling
  • Discriminant Function \>90
  • Autoimmune hepatitis
  • Hepatitis B, Hepatitis C, Human immunodeficiency Virus cases
  • Pregnancy
  • Hemophagocytic lymphohistiocytosis (HLH)
  • Hb\<8 and baseline White Blood Cell\>25000

Key Trial Info

Start Date :

September 7 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 27 2021

Estimated Enrollment :

126 Patients enrolled

Trial Details

Trial ID

NCT04066179

Start Date

September 7 2019

End Date

February 27 2021

Last Update

September 9 2019

Active Locations (1)

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Institute of Liver and Biliary Sciences

New Delhi, National Capital Territory of Delhi, India, 110070