Status:
TERMINATED
Detection of miRNAs in HPA Axis Function in Healthy Subjects
Lead Sponsor:
Cedars-Sinai Medical Center
Conditions:
Dexamethasone Effect on miRNA Profile in Healthy Humans
Eligibility:
All Genders
18+ years
Phase:
PHASE1
PHASE2
Brief Summary
The proposed study will test dexamethasone effect on miRNA profile in healthy humans. As our data indicate that miRNA levels change over time, the investigators will study the time course of miRNA res...
Eligibility Criteria
Inclusion
- Adults age ≥ 18
Exclusion
- Pregnancy
- Presence of a disease that affects HPA axis function
- Current use of medications that affect cortisol secretion, such as opioid pain medication, anti-fungal agents, anti-epileptic agents, and glucocorticoids, including hydrocortisone, prednisone, dexamethasone, steroid-containing inhalers, and steroid injected into the joints
- History of adverse event related to use of glucocorticoids
Key Trial Info
Start Date :
May 9 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 24 2019
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT04066647
Start Date
May 9 2019
End Date
July 24 2019
Last Update
July 17 2020
Active Locations (1)
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1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048