Status:

UNKNOWN

Sclerostin and Vascular Calcification in CKD and Renal Transplant

Lead Sponsor:

Ahmed Faisal Mohamed Mohamed Saleh

Conditions:

Vascular Calcification

Chronic Kidney Failure

Eligibility:

All Genders

18-70 years

Brief Summary

the aim of the research is to determine the degree of vascular calcification in chronic kidney disease and post-transplant and whether there is a correlation with the level of serum sclerostin.

Detailed Description

Sclerostin is a 22-kDa glycoprotein encoded by the SOST gene. This glycoprotein is almost exclusively synthesized by osteocytes that are not present near the bone surface but lie in the mineralized co...

Eligibility Criteria

Inclusion

  • Chronic Kidney disease stages 4 and 5
  • Renal transplant recipients

Exclusion

  • Significant co-morbidity: advanced cancer, advanced liver disease, tertiary hyperparathyroidism

Key Trial Info

Start Date :

December 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2020

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT04066855

Start Date

December 1 2019

End Date

September 1 2020

Last Update

August 26 2019

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