Status:

TERMINATED

Acupuncture Treatment of Chemotherapy-Induced Peripheral Neuropathy in Women

Lead Sponsor:

University of Utah

Conditions:

Chemotherapy-induced Peripheral Neuropathy

Breast Cancer Female

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

This pilot study aims to evaluate the feasibility to conduct a study of acupuncture treatment (AT) for Chemotherapy-Induced Peripheral Neuropathy (CIPN) at Huntsman Cancer Institute and to investigate...

Detailed Description

This pilot feasibility study aims to determine if conducting a trial of AT for CIPN is feasible at Huntsman Cancer Institute (HCI). The investigators aim to enroll and retain twenty participants who w...

Eligibility Criteria

Inclusion

  • Female age 18 or older.
  • Histologically proven breast, uterine, cervical or ovarian cancer of any stage.
  • Received either (1) a Paclitaxel treatment dose of at least 480 mg/m2 paclitaxel as a single or combination agent or (2) a Docetaxel treatment dose of at least 150 mg/m2 docetaxel as a single or combination agent. Treatment must be completed at least 3 months prior to enrollment.
  • Eligible participants report at least 1 month of altered sensation and/or pain in the feet (with or without presence in one or both hands) with a score of greater than or equal to 20 for CIPN on the sensory subscale of the CIPN-20 (scale 0-100).
  • Able to provide informed consent and willing to sign an approved consent form that conforms to federal and institutional guidelines.
  • Eastern Cooperative Oncology Group (ECOG) status of 0 (asymptomatic), 1 (symptomatic but completely ambulatory) or 2 (symptomatic, \<50% in bed during the day).

Exclusion

  • Preexisting neuropathy due to other identified etiologies includes diabetes, vitamin B12 deficiency, or alcoholism.
  • Having received more than 6 acupuncture treatments for any condition in the last six months.
  • Participants with claustrophobia, pacemakers, non-MRI compatible breast expanders or port-a-caths, neurostimulator devices, current pregnancy, exposure to shrapnel, left-handedness, or otherwise unsafe for MRI scanning.

Key Trial Info

Start Date :

November 5 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 12 2020

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT04067544

Start Date

November 5 2019

End Date

August 12 2020

Last Update

April 6 2025

Active Locations (1)

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1

Huntsman Cancer Institute

Salt Lake City, Utah, United States, 84112