Status:

COMPLETED

Impact of Pacing Mode and Diastolic Function on Cardiac Output

Lead Sponsor:

Kepler University Hospital

Collaborating Sponsors:

Medtronic

Conditions:

Diastolic Function

Cardiac Output

Eligibility:

All Genders

18-99 years

Phase:

NA

Brief Summary

Background It is known from previous research that in patients with complete AV (atrioventricular) block and pacemaker stimulation stroke volume and cardiac output are higher with AV-synchronous than ...

Eligibility Criteria

Inclusion

  • Patient is able and willing to give informed consent and is above the age of 18.
  • Patient is implanted with a dual chamber pacemaker system for at least 6 weeks.
  • Patient is in sinus rhythm on the day of recruitment.
  • Patient has a ventricular pacing rate exceeding 90%.
  • Upon initial device interrogation, parameters are within normal ranges.
  • Calculated battery life is more than 1 year.

Exclusion

  • Patient is not in sinus rhythm on the day of echo examination.
  • Intrinsic ventricular activation on the day of echo examination.
  • Relevant shunt on the atrial, ventricular or pulmonary level.
  • Moderate or severe heart valve dysfunction (stenosis or regurgitation).
  • Presence of other medical devices that may interact with the pacemaker system.
  • Women who are pregnant or breast feeding.

Key Trial Info

Start Date :

June 26 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 5 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04068233

Start Date

June 26 2019

End Date

February 5 2020

Last Update

February 21 2020

Active Locations (1)

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Kepler University Hospital

Linz, Upper Austria, Austria, 4020