Status:
UNKNOWN
Determining Bacterial Communities in the Lungs of HIV-infected Individuals With COPD in Uganda.
Lead Sponsor:
Makerere University
Conditions:
COPD
HIV/AIDS
Eligibility:
All Genders
35+ years
Brief Summary
Research question Is there any association between altered lung bacterial communities and HIV-associated Chronic Obstructive Pulmonary Disease (COPD)? Rationale Sub-Saharan Africa has experienced d...
Detailed Description
Background The improvements in access to antiretroviral therapy (ART) among people living with HIV/AIDs (PLWHA) has resulted in a decrease in HIV-associated morbidity and mortality. This is particula...
Eligibility Criteria
Inclusion
- Male and female individuals atleast 35 years of age
- Both HIV seropositive and seronegative.
- Spirometry confirmed COPD and no COPD
Exclusion
- Participants with asthma
- Participants with significant respiratory disease other than COPD
- Failure to perform spirometry
- Pulse rate greater than 120 beats per minute
- Blood pressure greater than 140(systolic)/90( diastolic)
- History of headaches in the past 6 months
- History of eye, chest or abdominal surgery
- History of hernia or chest trauma
- Pregnant women
- Bed ridden patients
- Mentally incapacitated patients
Key Trial Info
Start Date :
January 11 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2021
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04070248
Start Date
January 11 2019
End Date
February 1 2021
Last Update
August 30 2019
Active Locations (1)
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1
Makerere University Lung Institute
Kampala, Uganda, 256