Status:
RECRUITING
Correlation of Radiological Lesions With Vestibular Function in Patients With Bilateral Vestibulopathy
Lead Sponsor:
Jessa Hospital
Conditions:
Hearing Loss, Sensorineural
Bilateral Vestibular Deficiency
Eligibility:
All Genders
18-90 years
Brief Summary
In 2014 radiologic lesions were detected at one or more semicircular canals using CT and MR imaging of temporal bone in subjects carrying the p.P51S mutation in COCH. These lesions are believed to pre...
Eligibility Criteria
Inclusion
- must meet the Barany criteria for bilateral vestibulopathy: bilaterally pathological horizontal angu- lar VOR gain \<0.6, measured by the video-HIT5 or scleral-coil technique and/or
- reduced caloric response6 (sum of bither- mal max. peak SPV on each side \<6◦/sec7) and/or
- reduced horizontal angular VOR gain \<0.1 upon sinusoidal stimulation on a rota- tory chair (0.1 Hz, Vmax = 50◦ /sec) and a phase lead \>68 degrees (time constant \<5 sec).
- must be 18 or older
Exclusion
- \< 18 y
- does not meet Barany criteria for BV
- contraindication for CT and MR imaging
Key Trial Info
Start Date :
September 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 30 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04070937
Start Date
September 1 2019
End Date
October 30 2026
Last Update
August 25 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Jessa Hospital
Hasselt, Limburg, Belgium, 3500