Status:
UNKNOWN
Gastrostomy-Biliary Diversion: Innovative Management for Bile Canalicular Transport Disorders
Lead Sponsor:
National Liver Institute, Egypt
Conditions:
Progressive Familial Intrahepatic Cholestasis
Eligibility:
All Genders
1-18 years
Phase:
NA
Brief Summary
Progressive familial intrahepatic cholestasis (PFIC) is a group of disorders that can present early in life with cholestasis and intractable pruritus. Their treatment poses a great challenge, with med...
Detailed Description
Progressive familial intrahepatic cholestasis (PFIC) is a group of disorders that can present early in life with cholestasis and intractable pruritus. They result primarily from defective transporters...
Eligibility Criteria
Inclusion
- PFIC cases that are previously responding to medical treatment with recent flare of the disease that doesn't respond to medical therapy
- PFIC cases that are not responding to medical treatment and refusing non-transplant surgery and not indicated for liver transplant
- BRIC cases with frequent attacks not responding to medical therapy and refusing or unable to tolerate nasobiliary stent
Exclusion
- Severe portal hypertensive gastropathy
- Decompensated cirrhosis
Key Trial Info
Start Date :
March 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2021
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04071197
Start Date
March 10 2020
End Date
April 1 2021
Last Update
August 24 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Pediatric Hepatology, Gastroenterology and Nutrition Department, National Liver Institute, Menoufia University
Shibīn al Kawm, Menofiya, Egypt, 32511