Status:
ENROLLING_BY_INVITATION
Non-invasive Markers of Esophageal Function in Adults
Lead Sponsor:
Vanderbilt University Medical Center
Conditions:
Dysphagia
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The investigator proposes to study electrical activity reflective of esophageal motility in adults noninvasively by the use of multichannel electroesophagogram (EESG) and magnetoesophagogram (MESG) re...
Detailed Description
Dysphagia, or difficulty with swallowing, is a common symptom affecting nearly 9.4 million individuals or 4% of the US population. High resolution esophageal manometry is currently considered the gold...
Eligibility Criteria
Inclusion
- Adults ≥ 18 years of age who are undergoing HRM for routine standard of care evaluation for esophageal motility.
- Normal control participants (ages ≥ 18 years) who have no known gastrointestinal complications.
Exclusion
- Those with claustrophobia who cannot lie still under the SQUID for the length of time required
- Due to interference with signal acquisition, subjects with contraindication to undergoing an MRI scan as noted in the MRI Safety checklist by Vanderbilt University Medical Center (such as with heart pacemakers, metal implants, or metal chips or clips) will not undergo SQUID, but can still be eligible to do cutaneous EESG.
- Morbid obesity (these patients are potentially unable to lie under the current generation of SQUID devices)
- Patients with a history of cardiac arrhythmias or taking anticoagulants will be excluded
Key Trial Info
Start Date :
September 4 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04074356
Start Date
September 4 2019
End Date
September 1 2026
Last Update
September 5 2025
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232