Status:

COMPLETED

Locally Delivered Minocycline in Advanced Periodontitis

Lead Sponsor:

Mahsa University

Conditions:

Periodontitis, Adult

Eligibility:

All Genders

25-60 years

Phase:

PHASE4

Brief Summary

Local drug delivery provides higher concentrations in the availability of the drug at the specific infected sites with the advantage of sustained release. Periocline is a long acting , sustained relea...

Detailed Description

The subjects for this randomized controlled, parallel arm study will be selected from the primary health care in the Faculty of Dentistry, MAHSA University. In this clinical trial, 50 patients with ad...

Eligibility Criteria

Inclusion

  • systematically healthy patients with age range between 20- 60 years,
  • diagnosed with untreated Advanced Periodontitis with a pocket depth ≥6mm around two or more teeth, in two or more quadrants.

Exclusion

  • Patients given antibiotics or anti-inflammatory drugs in the past 6 months,
  • allergic to tetracycline,
  • pregnant or nursing females,
  • those using chlorhexidine or any other mouth rinse

Key Trial Info

Start Date :

June 25 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 20 2021

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04076098

Start Date

June 25 2018

End Date

September 20 2021

Last Update

September 23 2021

Active Locations (1)

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MAHSA University

Jenjarum, Selangor, Malaysia, 42610