Status:
UNKNOWN
Surgical Stages of Liver Cirrhosis In Patients With Hepatocellular Carcinoma
Lead Sponsor:
Chen Xiaoping
Conditions:
Hepatocellular Carcinoma
Liver Cirrhosis
Eligibility:
All Genders
18-75 years
Brief Summary
The investigators intend to perform a prospective, multicenter study to establish a set of clinical criteria for surgical stages of liver cirrhosis, which can be implemented to guide the surgical trea...
Detailed Description
HCC is the fifth most common malignancy in the world and ranks the third leading cause of tumor-related mortality. In China, more than 80% of HCC patients are accompanied by liver cirrhosis. Varied de...
Eligibility Criteria
Inclusion
- Male or female, 18 to 75 years of age, inclusive.
- Patients who are clinically diagnosed as hepatocellular carcinoma and confirmed by postoperative pathology.
- The liver function grade was Child-Pugh class A or class B, which can be restored to Child-Pugh class A within a short period of medical treatment.
- Patients who undergo open surgery.
- Patients have not been accompanied by serious physical diseases of heart, lung, brain, etc., and can generally tolerable for surgery.
- Ability to understand and the willingness to sign a written informed consent document.
Exclusion
- Patients with tumors that oppress the main portal vein or main portal vein thrombus.
- Patients that are accompanied with cavernous degeneration of portal vein.
- Patients with hypersplenism caused by diseases of the blood system.
- Patients suffer from serious acute and chronic diseases.
- Patients with severe infectious diseases.
- Patients with HIV-infectious or other AIDS-related disease.
- Patients are drug abusers or have any psychological or mental conditions that potentially lead to poor study compliance.
- Patients have any condition that in the judgement of the investigators would make the subject inappropriate for entry into this study.
Key Trial Info
Start Date :
August 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2020
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT04076631
Start Date
August 1 2019
End Date
December 1 2020
Last Update
October 12 2020
Active Locations (1)
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1
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030