Status:

TERMINATED

Assessment of the Utility of BIOMONITOR to Identify Atrial Fibrillation (AF) in Ablation Candidates Using Precise AF Detection

Lead Sponsor:

Biotronik, Inc.

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to evaluate the diagnostic utility of BIOTRONIK's subcutaneous cardiac rhythm monitor for the detection of AF prior to an ablation procedure.

Detailed Description

BIO-Precision is a post-market study investigating the utility of atrial fibrillation (AF) detection using BIOTRONIK's subcutaneous cardiac rhythm monitor, BIOMONITOR. The purpose of this study is to ...

Eligibility Criteria

Inclusion

  • Meet the indications for subcutaneous cardiac rhythm monitor insertion according to local regulations
  • Patient is able to understand the nature of the study and provide written informed consent
  • Inserted within the prior 30 days, or scheduled for insertion within 14 days, with BIOTRONIK's most current subcutaneous cardiac rhythm monitor
  • Diagnosed with paroxysmal atrial fibrillation and being evaluated for an AF ablation
  • Agree to wearing a 48 hr Holter monitor
  • Able and willing to complete all study visits at the study site for the study duration
  • Able and willing to use a CardioMessenger® and accepts Home Monitoring concept
  • Age greater than or equal to 18 years

Exclusion

  • Patient meets none of the indications for a BIOMONITOR
  • Patient is planned to have an ablation prior to BIOMONITOR insertion or 48 hr Holter monitoring visit
  • Patient is currently diagnosed with long-standing persistent or permanent AF
  • Patient is enrolled in another study that may change or alter the cardiac rhythm that occurs prior to the completion of the Holter
  • Currently indicated for or implanted with a pacemaker, ICD device, or hemodynamic monitoring system
  • Life expectancy less than 6 months
  • Patients reporting pregnancy at the time of enrollment
  • For patients enrolled after BIOMONITOR insertion:
  • • R-wave sensing \<0.25 mV according to the most recent remote or in-person device interrogation available prior to enrollment
  • After the pre-Holter observation period but prior to 48 hr Holter monitoring initiation, confirm the absence of the following exclusion criteria based on the remote interrogation collected at the end of the observation period:
  • No AF episodes observed or transmitted during pre-Holter observation period
  • R-wave sensing \<0.25 mV during pre-Holter observation period as reported by the 24 hr mean or mean value since last follow-up

Key Trial Info

Start Date :

September 25 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 24 2021

Estimated Enrollment :

84 Patients enrolled

Trial Details

Trial ID

NCT04076917

Start Date

September 25 2019

End Date

February 24 2021

Last Update

April 5 2022

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Cardiovascular Associates, Inc.

Kissimmee, Florida, United States, 34741

2

Florida Cardiology

Winter Park, Florida, United States, 32792

3

St. Louis Heart and Vascular

St Louis, Missouri, United States, 63136

4

The Ohio State University

Columbus, Ohio, United States, 43210