Status:

COMPLETED

Transgender Youth and PrEP: PK, Safety, Uptake & Adherence - Intervention Development

Lead Sponsor:

Hektoen Institute for Medical Research

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

HIV/AIDS

Gender

Eligibility:

All Genders

15-24 years

Brief Summary

To address the critical scientific gaps in PrEP safety for transgender youth and to plan for appropriate implementation of PrEP in transgender youth communities, the study will be conducted in 3 integ...

Detailed Description

Transgender women (TW) are one of the most vulnerable populations for acquiring HIV infection, and the scant available data on transgender men (TM) suggests they are also at risk. TW have accounted fo...

Eligibility Criteria

Inclusion

  • HIV uninfected
  • Able to provide informed consent in English
  • Self-reports HIV transmission risk behavior including one or more of the following: a) condomless anal or vaginal intercourse, b) 3 or more sexual partners in the past 3 months, c) any diagnosis by self-report of a STI in the past 12 months, and e) any history of transactional sex work

Exclusion

  • Hospitalization within 30 days of study entry (elective procedures okay with team approval)
  • Condition (medical, psychological, or social) that, in the opinion of the study investigators, would preclude the participant from completing study-required procedures
  • Previous participation in an HIV vaccine study, unless the participant can document placebo arm assignment
  • Use of TDF/FTC in the past 3 months

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 30 2023

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04077138

Start Date

January 1 2019

End Date

November 30 2023

Last Update

April 1 2024

Active Locations (3)

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Page 1 of 1 (3 locations)

1

University of Colorado, Denver

Denver, Colorado, United States, 80045

2

John H. Stroger, Jr. Hospital of Cook County

Chicago, Illinois, United States, 60612

3

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104