Status:
COMPLETED
Clinical and Prognostic Comparisons Between Invasive Pulmonary Aspergillosis With or Without Invasive Tracheobronchitis During Severe Influenza: a Retrospective Multicenter Cohort Study.
Lead Sponsor:
Centre Hospitalier Universitaire, Amiens
Collaborating Sponsors:
University Hospital, Lille
Centre Hospitalier de Lens
Conditions:
Invasive Pulmonary Aspergillosis
Morality
Eligibility:
All Genders
18+ years
Brief Summary
Invasive tracheobronchial aspergillosis (ITBA) is an uncommon, but severe clinical form of Invasive Pulmonary Aspergillosis (IPA) in which the fungal infection is entirely or predominantly confined to...
Detailed Description
Invasive pulmonary aspergillosis (IPA) is a well-known complication in severely immunocompromised hosts patients. Recent evidence has identified others populations at risk for IPA, including those wit...
Eligibility Criteria
Inclusion
- all ICU (Intensive care unit) patients
- patients aged from 18 years and more
- All patients hospitalized in ICU with a positive influenza RT-PCR extracted from the registry of the local virology department
- patients with a diagnosis of influenza confirmed by a positive influenza real time polymerase chain reaction (RT-PCR) from nasopharyngeal swab or bronchoalveolar lavage (BAL) fluid, with a concomitant diagnosis of proven or probable/putative IPA and the performing of a bronchoscopy
Exclusion
- minor or adult with guardianship
- absence of hospitalization in intensive care
- influenza infection not confirmed by PCR
Key Trial Info
Start Date :
July 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 16 2019
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT04077697
Start Date
July 1 2019
End Date
July 16 2019
Last Update
September 4 2019
Active Locations (1)
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1
CHU Amiens
Amiens, France, 80054