Status:
UNKNOWN
RISI in the Treatment of Recurrent Chest Wall Malignancies After EBRT
Lead Sponsor:
Peking University Third Hospital
Conditions:
Chest Wall Tumor
Eligibility:
All Genders
18-80 years
Brief Summary
This study will observe the efficacy and toxicities of 3-dimensional printing noncoplanar template assisted CT guided radioactive iodine-125 seeds implantation in the treatment of patients with recurr...
Detailed Description
Radioactive Iodine-125 seed brachytherapy is a conventional treatment in Peking University Third Hospital. Radioactive Iodine-125 seed brachytherapy is the implantation of Iodine-125 seed into tumors....
Eligibility Criteria
Inclusion
- histological proven malignant tumor
- tumor located in chest wall and lesion diameter \<= 10 cm
- recurrence after external beam radiotherapy
- there is no bleeding tendency
- there are no serious or uncontrolled underlying diseases (such as severe or uncontrolled hypertension, diabetes, cardiovascular and cerebrovascular diseases, and/or organ dysfunction
- there is an appropriate puncture path which is expected to achieve the treatment dose
- KPS \> 70, which is expected to be able to tolerate puncture/ brachytherapy, and the expected survival time is longer than 3 months
Exclusion
- there are skin ulceration, or with high risk of skin infection and ulceration
- liquefaction and necrosis in a large area in tumor with poor expected seeds distribution
- pregnant women, lactating women, psychiatric patients
- patients with poor compliance can not complete the treatment
- patients that researchers considered inappropriate to participate in this clinical trial
Key Trial Info
Start Date :
May 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04077710
Start Date
May 1 2020
End Date
April 30 2025
Last Update
December 27 2023
Active Locations (1)
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1
Peking University Third Hospital
Beijing, Beijing Municipality, China, 100191