Status:
RECRUITING
Regional or Extend LymphAdenectomy During Resection of Intrahepatic Cholangiocarcinoma
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Intrahepatic Cholangiocarcinoma
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Intrahepatic cholangiocarcinoma (ICC) is one of the common malignant tumors. Lymph node metastasis is an important factor affecting the poor prognosis of intrahepatic cholangiocarcinoma. The eighth ed...
Detailed Description
Expanding lymph node dissection can theoretically obtain more lymph node dissection. Obtaining enough lymph nodes can improve the accuracy of AJCC staging and accurately determine prognosis. However, ...
Eligibility Criteria
Inclusion
- Patients \>18 years of age and ≤80 years of age;
- Preoperative imaging and laboratory examination for intrahepatic cholangiocarcinoma, intraoperative frozen and postoperative pathology confirmed as intrahepatic cholangiocarcinoma; preoperative imaging assessment is resectable;
- No obvious lymph node metastasis in preoperative imaging; or negative intraoperative lymph node biopsy
- Liver function Child-Turcotte-Pugh score A-B grade;
- Residual liver volume \>30%; can tolerate radical hepatectomy
- The patient has autonomy, understands and voluntarily signs the written informed consent and is able to complete the follow-up plan;
- Sign the written informed consent form prior to the test screening.
Exclusion
- The patient has obvious heart, lung, brain and kidney dysfunction that affects the treatment of intrahepatic cholangiocarcinoma;
- The patient has a history of other malignant tumors;
- Liver function Child-Turcotte-Pugh score C;
- The investigator determined that it was not suitable for the study.
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
168 Patients enrolled
Trial Details
Trial ID
NCT04078230
Start Date
January 1 2020
End Date
December 31 2027
Last Update
November 9 2022
Active Locations (13)
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1
The Johns Hopkins Hospital
Baltimore, Maryland, United States, 10017
2
China-Japan Friendship Hospital
Beijing, Beijing Municipality, China
3
Chinese PLA General Hospital
Beijing, Beijing Municipality, China
4
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Guangzhou, Guangdong, China