Status:
UNKNOWN
Chinese Medicine Treat for Hypertensive Renal Injury
Lead Sponsor:
Jiangsu Province Hospital of Traditional Chinese Medicine
Collaborating Sponsors:
Ministry of Science and Technology of the People´s Republic of China
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Conditions:
Hypertension
Renal Injury
Eligibility:
All Genders
35-55 years
Phase:
PHASE2
PHASE3
Brief Summary
This study evaluates whether the traditional chinese medicine (Qianyangyuyin formula) could prevent and treat early renal injury in patients with hypertension and microalbuminuria (defined as a urinar...
Detailed Description
Hypertension is the main cardiovascular disease and the most important risk factor for severe lethal and disabling diseases such as stroke, myocardial infarction, heart failure, and chronic renal insu...
Eligibility Criteria
Inclusion
- Subject has primary hypertension(grades 2-3)
- Subject has microalbuminuria \[defined as a urinary albumin/creatinine ratio (UACR) between 30 and 300mg/g, and a eGFR at least 60ml/(min∙1.73m2)\]
- Subject has ascendant hyperactivity of liver Yang or Yin deficiency in TCM syndrome
- Subject voluntarily participates in the trial and signs informed consent
Exclusion
- Subject has secondary hypertension
- Subject with pregnancy or lactating
- Subject has serious life-threatening diseases, such as acute myocardial infarction, stroke, heart failure (NYHA IV), and malignant arrhythmia
- Subject's liver function (AST or ALT) is 2 times greater than normal value
- Subject has history of mental illness
- Subject currently participates in other drug clinical trials
Key Trial Info
Start Date :
September 10 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2021
Estimated Enrollment :
520 Patients enrolled
Trial Details
Trial ID
NCT04078711
Start Date
September 10 2019
End Date
December 30 2021
Last Update
September 6 2019
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