Status:
UNKNOWN
PR in Endoscopic LAR for Rectal Cancer
Lead Sponsor:
Southwest Hospital, China
Conditions:
Rectal Carcinoma
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The anastomotic leakage remains the major early complication after laparoscopic anterior resection(LAR) for medium \& low rectal cancer. Pelvic floor reconstruction (PR) is a key step in various stand...
Detailed Description
Eligible patients with rectal cancer will be randomly assigned to group with pelvic floor reconstruction(PR) versus group without pelvic floor reconstruction(NPR). We want to investigate the rate of ...
Eligibility Criteria
Inclusion
- patients with histologically proven rectal adenocarcinoma
- tumor located in the middle and lower rectum and anastomosis under the peritoneal reflection
- Tumor assessed as a depth of invasion that was confined to pT1-pT3, bN0-1M0 by ultrasound colonoscopy and/or pelvic MRI
- Negative circumferential resection margin confirmed by MRI
- Performance status (ECOG) 0\~1
- Written informed consent for participation in the trial
Exclusion
- History of accepting lower abdominal surgery.
- More than one colorectal tumor
- Patients with unresectable distant metastasis or multiple metastases
- Received neoadjuvant radiotherapy before surgery
- Signs of acute intestinal obstruction, bleeding or perforation needing emergency surgery
- Patients and/or family members cannot understand and accept this study
- Non-rectal adenocarcinoma was confirmed by postoperative pathological examination
Key Trial Info
Start Date :
September 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2022
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04078828
Start Date
September 1 2019
End Date
April 1 2022
Last Update
November 30 2021
Active Locations (1)
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1
General Surgery Center of PLA
Chongqing, Chongqing Municipality, China, 400038