Status:

UNKNOWN

SMOFlipid and Incidence of BPD in Preterm Infants

Lead Sponsor:

University of Calgary

Conditions:

Very Low Birth Weight Infant

Bronchopulmonary Dysplasia

Eligibility:

All Genders

1-48 years

Phase:

NA

Brief Summary

Despite many advances in neonatal care in the recent years, bronchopulmonary dysplasia (BPD) continues to be the major cause of chronic lung morbidity in infants. The pathogenesis of BPD is multifacto...

Detailed Description

Intravenous lipid emulsions (IVLEs) is a core component of parenteral nutrition (PN) for providing calories and essential fatty acids. Until recently, Intralipid was the only available IVLE in North A...

Eligibility Criteria

Inclusion

  • Preterm infants born \<30 weeks and admitted to NICU at Foothills Medical Centre in the first 24 hours of life.
  • Anticipated duration of PN for \>7 days

Exclusion

  • Infants with congenital anomalies
  • Infants with suspected inborn errors of metabolism or family history of inborn error of metabolism
  • Perinatal asphyxia
  • Evidence of congenital infection
  • Primary biliary atresia

Key Trial Info

Start Date :

December 16 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2024

Estimated Enrollment :

384 Patients enrolled

Trial Details

Trial ID

NCT04078906

Start Date

December 16 2019

End Date

October 1 2024

Last Update

November 7 2022

Active Locations (1)

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1

Foothills Medical Centre

Calgary, Alberta, Canada, T2N 2T9