Status:
TERMINATED
Glucagon Response to Prandial Insulin Administration in Persons With Type 1 Diabetes
Lead Sponsor:
Washington University School of Medicine
Conditions:
Type 1 Diabetes
Hyperglycemia, Postprandial
Eligibility:
All Genders
18-90 years
Phase:
PHASE1
PHASE2
Brief Summary
Glucagon regulation and response in persons with T1D at the basal state and in response to various stimuli remains unclear. Dr. Philip Cryer has previously reported that, in T1D young adults with a co...
Detailed Description
Glucagon regulation and response in persons with T1D at the basal state and in response to various stimuli remains unclear. Dr. Philip Cryer has previously reported that, in T1D young adults with a co...
Eligibility Criteria
Inclusion
- 10 persons with T1D for \>5 years age \>18.
- HbA1c \<9.5%
- Patients using either MDI or insulin pumps will be included.
- Patients using CGM will continue the use during the study, however glucoses will be measured by laboratory methods.
- Persons of all races, ethnicity and genders will be included
- Participants should have normal hemoglobin, hematocrit and eGFR \>60 ml/min/1.73m2.
Exclusion
- Persons with type 2 diabetes, monogenic diabetes, pancreatic diseases.
- Pregnancy, prisoners, other vulnerable populations or persons unable to understand the protocol and provide written informed consent.
- Persons who take daily steroids, any route, for any purpose
Key Trial Info
Start Date :
February 13 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2020
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT04079881
Start Date
February 13 2020
End Date
July 1 2020
Last Update
October 7 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Washington University in St Louis
St Louis, Missouri, United States, 63110