Status:
COMPLETED
Therapeutic Drug Monitoring of Guselkumab in Psoriasis Patients
Lead Sponsor:
University Hospital, Ghent
Collaborating Sponsors:
KU Leuven
University Ghent
Conditions:
Psoriasis Vulgaris
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Biologic such as guselkumab are currently the most effective treatment option for patients with moderate to severe psoriasis. But they are costly for healthcare systems and still described according t...
Detailed Description
Patients will be included after signing informed consent. After inclusion, patients will continue on standard dosing schedule of guselkumab (i.e. one loading dose (100 mg) at week 0 and week 4 and fol...
Eligibility Criteria
Inclusion
- Participants must have a clinical or histological diagnosis of chronic plaque-type psoriasis
- Participants must sign an ICF indicating that he or she understands the purpose of, and procedures required for, the study and is willing to participate in the study
Exclusion
- Participants who have currently a predominant nonplaque form of psoriasis
- Participants who are pregnant, nursing or planning a pregnancy
- Participants who are unable or unwilling to undergo multiple venapunctures
- Participants who are treated according to a different dosing schedule than standard dosing of guselkumab
Key Trial Info
Start Date :
June 27 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT04080648
Start Date
June 27 2018
End Date
December 31 2023
Last Update
September 19 2024
Active Locations (7)
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1
AZ Maria Middelares
Ghent, East-Flanders, Belgium, 9000
2
AZ Sint-Lucas
Ghent, East-Flanders, Belgium, 9000
3
University Hospital Ghent
Ghent, East-Flanders, Belgium, 9000
4
Private practice Dermatology
Maldegem, East-Flanders, Belgium, 9990