Status:
UNKNOWN
Using DBS to Probe Basal Ganglia Dysfunction
Lead Sponsor:
University of Oxford
Conditions:
Parkinson's Disease
Tremor
Eligibility:
All Genders
18-80 years
Brief Summary
This study will probe the function of collections of neurons deep in the brain termed the basal ganglia It will investigate the role of the basal ganglia in how and why movement is disrupted in condit...
Detailed Description
This study investigates how the basal ganglia contribute to motor symptoms like tremor, bradykinesia and muscle spasm. The basic research approach is to record from sites in the basal ganglia whilst p...
Eligibility Criteria
Inclusion
- Participant is willing and able to give informed consent for participation in the study.
- Male or Female, aged 18 to 80 years old.
- Diagnosed with Parkinson's disease, Essential Tremor or Dystonia.
- Undergoing two-stage surgery for deep brain stimulation as therapy for their movement disorder.
Exclusion
- Cognitive impairment (judged by the clinician on the care team or in the research team as a participant not having sufficient mental capacity to understand the study and its requirements). This includes anyone who, in the opinion of clinicians on the care team or clinicians in the research team, is unlikely to retain sufficient mental capacity for the duration of their involvement in the study.
- Intracranial bleeding, confusion, cerebrospinal fluid leak or any other complication after the first stage of surgery.
Key Trial Info
Start Date :
December 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04080674
Start Date
December 1 2019
End Date
November 30 2023
Last Update
September 6 2019
Active Locations (1)
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1
University of Oxford
Oxford, United Kingdom, OX3 9DU