Status:
COMPLETED
The Moderating Roles of Social Support, Coping Resources and Personality and Mediating Role of Self-esteem on the Impact of Cognitive Deficit on Neuropsychiatric Symptoms Among Persons With Mild Cognitive Impairment: A Mixed-method Sequential Explanatory Design
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Mild Cognitive Impairment
Behavioral Symptoms
Eligibility:
All Genders
18+ years
Brief Summary
This is a sequential mixed study to test the hypothesized models with seven hypotheses of the relationship between cognitive deficit (subject and objective) and neuropsychiatric symptoms (NPS) among p...
Detailed Description
The primary aim of this study is to test the hypothesized model that explores the moderating roles of neurotic personality, social support and coping style, as well as the mediating role of self-estee...
Eligibility Criteria
Inclusion
- Aged 18 years old or above
- Able to communicate in Cantonese
- Diagnosis with MCI as defined by the following criteria:
- Presence of significant cognitive complaints, as defined by more than three complaints on the Memory Inventory for Chinese (MIC), which is a 27-item instrument measuring subjective memory deficit
- Abnormal objective cognitive performance defined as \< 1.5 standard deviations from age and education matched normal persons on Hong Kong Chinese version of Montreal Cognitive Assessment (HK-MoCA), which is a 12-item instrument measuring cognitive functions
- Independence in daily living as evaluated through clinical interview
- Both patients and one of their guardian or family members are consented to participate in the study
Exclusion
- With the confirmed diagnosis of any forms of dementia
- With the confirmed diagnosis of psychiatric morbidities, or history with stroke, brain injury and other neurological conditions that may affect cognitive, behavioural and emotional functioning which may confound outcome measurement and limit their participation in the study
- With hearing or visual impairment that may hinder participation in research activities
- Current use of cognitive intervention or electromagnetic stimulation
Key Trial Info
Start Date :
March 29 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 29 2020
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT04085107
Start Date
March 29 2020
End Date
December 29 2020
Last Update
January 20 2021
Active Locations (1)
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1
University of Hong Kong
Hong Kong, Hong Kong