Status:
COMPLETED
VNS-supplemented Motor Retraining After Stroke
Lead Sponsor:
University of Pittsburgh
Conditions:
Stroke, Acute
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The goal of this study is to learn more about the connections between the brain, spinal cord, and muscles and how these connections can be strengthened after neurological injury.
Detailed Description
To establish a link between the physiological mechanisms driving enhanced motor control in response to VNS, subjects will undergo progressive training on a visuomotor task that requires fine gradation...
Eligibility Criteria
Inclusion
- INDIVIDUALS WHO HAVE HAD A STROKE:
- Diagnosis of first ever stroke
- At least 6 months after stroke onset
- Motor-evoked potentials in hand/arm muscles
- Subjects must show an understanding of the study goals and have the ability to follow simple directions as judged by the investigators.
- ALL INDIVIDUALS:
- Between the ages of 18 and 75 years old
Exclusion
- INDIVIDUALS WHO HAVE HAD A STROKE:
- Hemispatial neglect, aphasia, or cognitive impairment that would impact testing and would interfere with the ability to follow simple instructions, as judged by the investigators
- ALL INDIVIDUALS:
- Neurological disorder(s) influencing movement (besides stroke)
- History of seizure or epilepsy
- Metallic brain implants
- Bodily implants such as cardioverter defibrillators, insulin pumps, ventriculoperitoneal shunts, cochlear implants, or pacemakers
- Pregnant or expecting to become pregnant
- Difficulty maintaining alertness and/or remaining still
- Silicone or plastic allergy
- History of vestibular disorders (eg, Vertigo, Meniere's Disease, etc.)
Key Trial Info
Start Date :
September 22 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 9 2021
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT04088578
Start Date
September 22 2019
End Date
November 9 2021
Last Update
November 1 2022
Active Locations (1)
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1
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213