Status:

COMPLETED

Comparison of Effectiveness Between the Combination of Lidocaine Sprayed at Laryngeal Inlet and on the Cuff of Endotracheal Tube Versus Intravenous Lidocaine for Reducing Cough During Extubation

Lead Sponsor:

Khon Kaen University

Conditions:

Reducing Cough During Extubation

Eligibility:

All Genders

19-60 years

Phase:

NA

Brief Summary

Coughing during extubation of endotracheal tube (ETT) is a common problem that leads to poor surgical results including hemodynamic change, rebleeding at the surgical wound and wound dehiscence. Recen...

Detailed Description

A prospective randomized control trial was conduct with 164 patients. They were randomly allocated into Gr. A and B. Group A received four puffs of 10% lidocaine sprayed at the cuff of ETT and four pu...

Eligibility Criteria

Inclusion

  • patients who underwent elective surgery with American Society of Anesthesiologists physical status classifications of I and III

Exclusion

  • patients having body mass index more than 35 kg/m2, high risk of aspiration, chronic smokers more than ten pack-years, chronic cough or recent upper respiratory infection, suspected difficult airway, retained ETT prior surgery, surgery at oral cavity, neck and thoracic region, operative time more than 120 minutes or less than 30 minutes, and history of lidocaine allergy

Key Trial Info

Start Date :

September 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 30 2019

Estimated Enrollment :

164 Patients enrolled

Trial Details

Trial ID

NCT04090112

Start Date

September 1 2018

End Date

June 30 2019

Last Update

September 16 2019

Active Locations (1)

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Khon Kaen University

Khon Kaen, Thailand, 40002