Status:

UNKNOWN

Optimisation of Radiotherapy in Rectal Cancer (ORREC)

Lead Sponsor:

University of Manchester

Collaborating Sponsors:

The Christie NHS Foundation Trust

Conditions:

Rectal Adenocarcinoma

Eligibility:

All Genders

18+ years

Brief Summary

This is a retrospective study using images acquired routinely for diagnosis of rectal cancer to see if these could be used to predict responses to radiotherapy treatment and if it can, whether the tre...

Detailed Description

The treatment of locally advanced rectal cancer is primarily radiotherapy (+/- chemotherapy) followed by surgery. The reason for radiotherapy is to reduce the risk of recurrence after surgery or to sh...

Eligibility Criteria

Inclusion

  • Histologically confirmed rectal adenocarcinoma.
  • Received pelvic radiotherapy (+/- chemotherapy) as neo-adjuvant treatment
  • Age 18 and above

Exclusion

  • Other rectal pathologies.
  • Patients less than 18yrs at diagnosis.

Key Trial Info

Start Date :

September 23 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 31 2021

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT04090450

Start Date

September 23 2019

End Date

March 31 2021

Last Update

September 16 2019

Active Locations (1)

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1

Christie Hospital NHS Foundation Trust

Manchester, England, United Kingdom, M20 4BX