Status:
UNKNOWN
Efficacy of Short Pulsed 1064 nm Nd-YAG Laser Versus 10600 nm Fractional CO2 Laser in Treatment of Striae Alba
Lead Sponsor:
Cairo University
Conditions:
Striae Distensae
Striae; Albicantes
Eligibility:
All Genders
14-50 years
Phase:
NA
Brief Summary
Striae alba is a clinical variant of striae distensae characterized by focal dermal collagen loss and thinning of elastic fibers. Carbon dioxide (CO2) laser is an ablative laser modality that ablates ...
Detailed Description
Striae distensae (SD) are skin disorders characterized by linear parallel edematous plaques that evolve into atrophic depressions in areas of dermal damage. They commonly develop on sites of skin stre...
Eligibility Criteria
Inclusion
- Patients with striae alba.
- Ages between 14 years - 50 years.
- Both sexes.
- Skin types I-IV
- Bilateral striae.
Exclusion
- Patients with striae rubra, striae nigra, striae caerulea or striae atrophicans.
- History of diseases associated with SD (cushing disease or Marfan syndrome).
- History of drugs associated with development of SD (topical or systemic glucocorticoids, Indinavir or protease inhibitors).
- History of conditions with abnormal dermal connective tissue structure (Ehler-Danlos syndrome, cutis laxa, pseudoxanthoma elasticum, elastolysis, elastomas, hyaline fibromatosis, keloidal tendencies, skin atrophy, poikiloderma or anetoderma).
- Current state of pregnancy in female patients.
- Relative contraindications to laser therapy (photosensitive dermatoses or burns).
- History of any therapeutic procedure for striae in the past 6 months before enrollment in the study.
- History of conditions associated with dermal edema or lymphedema.
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT04092881
Start Date
February 1 2019
End Date
December 31 2021
Last Update
November 17 2020
Active Locations (1)
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1
Cairo University
Cairo, Egypt, 35855