Status:
COMPLETED
The Relevance of the Blood-brain Barrier to Cognitive Dysfunction and Alzheimer's Disease
Lead Sponsor:
Charite University, Berlin, Germany
Collaborating Sponsors:
Prof. Dr. med. Jochen Fiebach (Senior Physician)
Conditions:
Blood Brain Barrier
Alzheimer Disease
Eligibility:
All Genders
50+ years
Brief Summary
This study attempts to replicate the findings published in Nature Medicine by Nation and colleagues (2019). By using a large observational cohort (DZNE - Longitudinal Cognitive Impairment and Dementia...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- \- ≥ 50 years with neuropsychologically confirmed no cognitive dysfunction, mild cognitive impairment or mild dementia
- Exclusion cirteria:
- no current or prior history of any neurological or psychiatric condition, which might affect cognitive function
- no neurodegenerative disease other than AD
- specifically no extensive vascular white matter dementia or vascular dementia
Exclusion
Key Trial Info
Start Date :
September 12 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2021
Estimated Enrollment :
101 Patients enrolled
Trial Details
Trial ID
NCT04093882
Start Date
September 12 2019
End Date
September 30 2021
Last Update
November 11 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Charité Universitätsmedizin Berlin
Berlin, Germany, 10117