Status:
COMPLETED
Effect of Community Active Case Finding Strategies for Detection of Tuberculosis in Cambodia
Lead Sponsor:
National University of Singapore
Collaborating Sponsors:
KHANA Center for Population Health Research
Conditions:
Tuberculosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Tuberculosis (TB) is a highly stigmatized disease, and approximately one-third of the Cambodian population living with TB are undetected. Therefore, it is vital to find these missing cases and promptl...
Detailed Description
Tuberculosis (TB) is a leading infectious cause of morbidity and mortality worldwide, accounting for 10 million new cases and 1.6 million deaths in 2017. The disease burden is disproportionately conce...
Eligibility Criteria
Inclusion
- Presumptive TB cases will be referred to the health centers for TB screening and diagnosis in the intervention arms and self-presented to the health centers in the control arm. We will include the aggregated number of cases diagnosed and notified from all arms regardless of age. In this project, an individual is defined as a presumptive TB case if he/she exhibits any of the following symptoms19:
- Pulmonary TB (PTB): A cough more than two weeks and at least one general symptom
- Extra-pulmonary TB (EPTB): Presence of symptoms, depending on the location of TB, (e.g., cervical lymph node, swollen backbone, swollen articulation, etc.) and at least one general symptom
- General symptoms: Fever, night sweat for more than two weeks or unintentional weight loss (\>5% reduction in usual body weight over the last 6 to 12 months)20
- People newly diagnosed with TB age 18 and above\* from the selected health centers. We will only include all people with TB aged 18 years or over with TB (all-forms) for the baseline and follow-up survey.
Exclusion
- We will exclude those who refused to participate.
Key Trial Info
Start Date :
December 16 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2022
Estimated Enrollment :
2004 Patients enrolled
Trial Details
Trial ID
NCT04094350
Start Date
December 16 2019
End Date
January 31 2022
Last Update
November 29 2022
Active Locations (3)
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1
KHANA Center for Population Health Research
Phnom Penh, Cambodia, 2361
2
Cambodia Anti-Tuberculosis Association
Phnom Penh, Cambodia, 2589-384
3
National Center for Tuberculosis and Leprosy Control
Phnom Penh, Cambodia, 2589