Status:
COMPLETED
Malaria High-Risk Populations in Namibia
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
University of Namibia
Ministry of Health and Social Services, Namibia
Conditions:
Malaria
Eligibility:
All Genders
6+ years
Phase:
PHASE4
Brief Summary
This study aims to determine the effectiveness, cost-effectiveness, acceptability, and feasibility of targeted delivery of a package of malaria interventions for improving effective coverage and reduc...
Detailed Description
This study is the second phase of work in Zambezi and Ohangwena Regions, Namibia, building off a formative phase of work that characterized the risk behaviors migratory patterns, health-seeking behavi...
Eligibility Criteria
Inclusion
- HRP study populations (all)
- Study participants include those in the 8 selected health facility catchment areas within Zambezi and Ohangwena Regions.
- Identify primary occupation as a agricultural worker or cattle herder
- Zambezi Region: Have slept or worked outside at a farm or cattle post in the past 7 days or will do over the next 3 weeks (sleeping outside, working outside ploughing or guarding crops/cattle, or sleeping in any type of structure located at a farm or cattle post site)
- Ohangwena Region: Report overnight travel to Angola for grazing cattle during the malaria transmission season (November to May) Be willing and able to provide consent (ie mentally fit)
- Presumptive AL treatment
- In addition to the above, subjects must report travel outside of Namibia within the past 60 days to be eligible to receive AL.
- Enhanced vector control
- In addition to the above, participants must not sleep in a structure sprayed with insecticide to be eligible to receive an LLIN or sprayed tent/tarp.
- Focus group discussions and key informant interviews
- Meet eligibility criteria as a member of an HRP, health facility staff or health extension worker involved in the diagnosis and treatment of HRP populations.
- Individuals must be 18 years and older and willing and able to provide consent to be included in the GPS logger, focus group discussions or key informant interviews
Exclusion
- Per national guidelines in Namibia, presumptive treatment with AL will not be given to women who are pregnant in the first trimester, individuals weighing less than 5kg, those with a known AL allergy or suspected severe malaria.
- Individuals under the age of 18 will be excluded from the GPS logger study, focus group discussions and key informant interviews.
Key Trial Info
Start Date :
October 31 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2020
Estimated Enrollment :
3302 Patients enrolled
Trial Details
Trial ID
NCT04094727
Start Date
October 31 2019
End Date
June 30 2020
Last Update
November 3 2020
Active Locations (1)
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1
University of Namibia, Multidisciplinary Research Centre
Windhoek, Namibia