Status:

RECRUITING

RCT: Mako Medial Unicondylar Knee Arthroplasty vs Oxford Unicondylar Knee Arthroplasty

Lead Sponsor:

University College, London

Collaborating Sponsors:

Stryker Instruments

Conditions:

Unicompartmental Knee Replacement

Osteo Arthritis Knee

Eligibility:

All Genders

40-80 years

Phase:

NA

Brief Summary

The overall aim of this prospective, randomised, single-blinded, controlled trial is to compare clinical outcomes and accuracy of implant positioning in Mako robotic UKA versus jig-based Oxford UKA wi...

Eligibility Criteria

Inclusion

  • • Patient has medial unicompartmental knee osteoarthritis requiring primary UKA
  • Patient and Surgeon are in agreement that UKA is the most appropriate treatment
  • Patient is fit for surgical intervention following review by surgeon and anaesthetist
  • Patient is between 40-80 years of age at time of surgery
  • Gender: male and female
  • Patient must be capable of giving informed consent and agree to comply with the postoperative review program
  • Patient must be a permanent resident in an area accessible to the study site
  • Patient must have sufficient postoperative mobility to attend follow-up clinics and allow for radiographs to be taken

Exclusion

  • • Patient is not suitable for primary UKA e.g. multi-compartmental knee osteoarthritis, anterior cruciate ligament rupture
  • Patient is not medically fit for surgical intervention
  • Patient requires revision surgery following previously failed correctional osteotomy or ipsilateral UKA
  • Patient is immobile or has another neurological condition affecting musculoskeletal function
  • Patient is less than 40 years of age or greater than 80 years of age
  • Patient is already enrolled on another concurrent clinical trial
  • Patient is unable or unwilling to sign the informed consent form specific to this study
  • Patient is unable to attend the follow-up programme
  • Patient is non-resident in local area or expected to leave the catchment area postoperatively

Key Trial Info

Start Date :

November 24 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT04095637

Start Date

November 24 2017

End Date

January 1 2026

Last Update

July 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UCL Hospital NHS Foundation Trust

London, United Kingdom, NW1 2BU