Status:
COMPLETED
Cabergoline Before or After Oocyte Collection for Follicular Resolution
Lead Sponsor:
Fertility Center of Las Vegas
Conditions:
Infertility, Female
Eligibility:
FEMALE
18+ years
Phase:
PHASE4
Brief Summary
Randomized trial comparing the efficacy of two different times of administration of cabergoline in patients undergoing controlled ovarian stimulation and oocyte collection.
Eligibility Criteria
Inclusion
- Adult female at least 18 years of age intending to undergo ovarian stimulation for a cycle of IVF.
- Ability read and understand English sufficiently to obtain informed consent and complete a study diary.
- Pre-implantation genetic screening (PGS) is allowed.
- Egg donors are allowed.
- Patients using a gestational carrier are allowed.
- Patients with prior IVF cycles are allowed, but no patient can undergo more than one cycle with oocyte collection under this study.
Exclusion
- Egg banking, donor egg banking, or any cycle type that would preclude immediate culture to blastocyst stage.
- Patients that would be unavailable for the follow-up ultrasound 5 days post-retrieval, such as patients that live far from the clinic (e.g. out of state).
- Uncontrolled hypertension.
- Ergot alkaloid hypersensitivity or allergy.
- History of pulmonary, pericardial, retroperitoneal fibrotic disorders.
- History of bipolar disorder, schizophrenia, or psychotic illness.
- Breast feeding.
- History of eclampsia or pre-eclampsia.
- Severe hepatic dysfunction.
- Current use of any dopamine receptor agonist or antagonist for any purpose, including, but not limited to, cabergoline (Dostinex), aripiprazole (Abilify), bromocriptine (Parlodel), methylphenidate (Ritalin), buproprion (Wellbutrin, Zyban), lisdexamfetamine (Vyvanse).
- Any condition that, in the opinion of the physician or principal investigator, would place the patient at undue risk under this protocol or would otherwise make the protocol inappropriate for that subject.
Key Trial Info
Start Date :
September 23 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 10 2021
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT04096027
Start Date
September 23 2019
End Date
June 10 2021
Last Update
June 14 2021
Active Locations (1)
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1
Fertility Center of Las vegas
Las Vegas, Nevada, United States, 89117