Status:
TERMINATED
Mapping Draining Lymph Nodes in CNS Malignancies
Lead Sponsor:
Washington University School of Medicine
Collaborating Sponsors:
Lloyd J. Old STAR Program
Conditions:
Central Nervous System Neoplasms
Central Nervous System Tumor
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
The purpose of this research study is to determine whether the lymph nodes that drain a brain tumor can be detected by imaging after injection of a substance called Tc-99m tilmanocept directly into th...
Eligibility Criteria
Inclusion
- Candidate for surgical resection or stereotactic biopsy of suspected brain tumor, including benign tumors (e.g., meningioma) and malignant tumors (e.g., glioma or metastatic disease).
- Suitable candidate to receive Tc-99m tilmanocept injection and study related imaging post-operatively per the Principal Investigator and/or treating neurosurgeon.
- At least 18 years of age.
- Willing and able to provide informed consent (or consent of legally authorized representative).
Exclusion
- Documented hypersensitivity to dextran and/or modified forms of dextran.
- Pregnant.
- Prior surgical evacuation of lymph nodes of the head and/or neck
Key Trial Info
Start Date :
December 3 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2022
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT04096716
Start Date
December 3 2019
End Date
April 30 2022
Last Update
December 21 2023
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110